JN.11 (BA.2.86.1+S:V1104L)with S:L455S (25 sequences 8 countries)

[xz-keg]

It seems that there's another BA.2.86+S:V1104L branch likely emerged in SE Asia, with S:L455S it effectively reproduces the current fastest spike of JN.1.11.

BA.2.86.1+G24872T(S:V1104L)

GISAID query:A6183G,G24872T,-27810,-7528,-8456,-A405G
No. of seqs: 72(Australia 9 Canada 1 UK 1 France 6 Indonesia 3 Japan 6 Malaysia 1 Singapore 21(1 from Malaysia), South Korea 6 Sweden 1 USA 15(1 from UAE) China 1 Vietnam 1)

First: EPI_ISL_18499092, USA, 2023-10-3
Latest: EPI_ISL_18757342, USA, 2023-1-8

GISAID query for S:L455S branch: A6183G,G24872T,-27810,-7528,-8456,-A405G, ,-T3565C,T22926C (4 seqs, Singapore, Japan, USA)

usher
Note that some are on other artefact branches.

[FedeGueli]

+1 Thailand. great catch btw! it appears that S:V1104L is beneficial in BA.2.86
and it is predicted to be good by Bloom/Neher,

While Dadonaite/Bloom predicts it to affect ace2 binding.

[xz-keg]

+1 USA airport seq on S:L455S branch , origin country unknown.