'lose'

[jmccrae]

Synsets
oewn-02292634-v (Interlingual Index: i33171)
(v) lose fail to keep or to maintain; cease to have, either physically or in an abstract sense “She lost her purse when she left it unattended on her seat”

oewn-02292463-v (Interlingual Index: i33170)
(v) lose miss from one's possessions; lose sight of “I've lost my glasses again!”

Motivation
I cannot figure out what distinction in sense was meant here. The first synset is more widely used in resources such as SemCor

[arademaker]

The antonym relations can give some clues. One also has the frame Something ----s something

[jmccrae]

Okay, so one of the meanings is the opposite of 'keeping' and the other is the opposite of 'finding'. This would suggest that one sense is more active, however I still don't see this as a meaningful sense distinction.