allow manylinux compatibility override via _manylinux module.

crates/bench/benches/uv.rs

@@ -127,8 +127,9 @@ mod resolver {
         Arch::Aarch64,
     );
 
-    static TAGS: LazyLock<Tags> =
-        LazyLock::new(|| Tags::from_env(&PLATFORM, (3, 11), "cpython", (3, 11), false).unwrap());
+    static TAGS: LazyLock<Tags> = LazyLock::new(|| {
+        Tags::from_env(&PLATFORM, (3, 11), "cpython", (3, 11), false, false).unwrap()
+    });
 
     pub(crate) async fn resolve(
         manifest: Manifest,

crates/platform-tags/src/tags.rs

@@ -94,10 +94,19 @@ impl Tags {
         python_version: (u8, u8),
         implementation_name: &str,
         implementation_version: (u8, u8),
+        manylinux_compatible: bool,
         gil_disabled: bool,
     ) -> Result<Self, TagsError> {
         let implementation = Implementation::parse(implementation_name, gil_disabled)?;
-        let platform_tags = compatible_tags(platform)?;
+
+        // Determine the compatible tags for the current platform.
+        let platform_tags = {
+            let mut platform_tags = compatible_tags(platform)?;
+            if matches!(platform.os(), Os::Manylinux { .. }) && !manylinux_compatible {
+                platform_tags.retain(|tag| !tag.starts_with("manylinux"));
+            }
+            platform_tags
+        };
 
         let mut tags = Vec::with_capacity(5 * platform_tags.len());
 
@@ -931,6 +940,64 @@ mod tests {
         );
     }
 
+    /// Ensure the tags returned do not include the `manylinux` tags
+    /// when `manylinux_incompatible` is set to `false`.
+    #[test]
+    fn test_manylinux_incompatible() {
+        let tags = Tags::from_env(
+            &Platform::new(
+                Os::Manylinux {
+                    major: 2,
+                    minor: 28,
+                },
+                Arch::X86_64,
+            ),
+            (3, 9),
+            "cpython",
+            (3, 9),
+            false,
+            false,
+        )
+        .unwrap();
+        assert_snapshot!(
+            tags,
+            @r###"
+        cp39-cp39-linux_x86_64
+        cp39-abi3-linux_x86_64
+        cp39-none-linux_x86_64
+        cp38-abi3-linux_x86_64
+        cp37-abi3-linux_x86_64
+        cp36-abi3-linux_x86_64
+        cp35-abi3-linux_x86_64
+        cp34-abi3-linux_x86_64
+        cp33-abi3-linux_x86_64
+        cp32-abi3-linux_x86_64
+        py39-none-linux_x86_64
+        py3-none-linux_x86_64
+        py38-none-linux_x86_64
+        py37-none-linux_x86_64
+        py36-none-linux_x86_64
+        py35-none-linux_x86_64
+        py34-none-linux_x86_64
+        py33-none-linux_x86_64
+        py32-none-linux_x86_64
+        py31-none-linux_x86_64
+        py30-none-linux_x86_64
+        cp39-none-any
+        py39-none-any
+        py3-none-any
+        py38-none-any
+        py37-none-any
+        py36-none-any
+        py35-none-any
+        py34-none-any
+        py33-none-any
+        py32-none-any
+        py31-none-any
+        py30-none-any
+        "###);
+    }
+
     /// Check full tag ordering.
     /// The list is displayed in decreasing priority.
     ///
@@ -951,6 +1018,7 @@ mod tests {
             (3, 9),
             "cpython",
             (3, 9),
+            true,
             false,
         )
         .unwrap();
@@ -1575,6 +1643,7 @@ mod tests {
             "cpython",
             (3, 9),
             false,
+            false,
         )
         .unwrap();
         assert_snapshot!(

crates/uv-python/python/get_interpreter_info.py

@@ -542,6 +542,17 @@ def main() -> None:
         "python_version": ".".join(platform.python_version_tuple()[:2]),
         "sys_platform": sys.platform,
     }
+    os_and_arch = get_operating_system_and_architecture()
+
+    manylinux_compatible = True
+    if os_and_arch["os"]["name"] == "manylinux":
+        # noinspection PyProtectedMember
+        from .packaging._manylinux import _get_glibc_version, _is_compatible
+
+        manylinux_compatible = _is_compatible(
+            arch=os_and_arch["arch"], version=_get_glibc_version()
+        )
+
     interpreter_info = {
         "result": "success",
         "markers": markers,
@@ -554,7 +565,8 @@ def main() -> None:
         "stdlib": sysconfig.get_path("stdlib"),
         "scheme": get_scheme(),
         "virtualenv": get_virtualenv(),
-        "platform": get_operating_system_and_architecture(),
+        "platform": os_and_arch,
+        "manylinux_compatible": manylinux_compatible,
         # The `t` abiflag for freethreading Python.
         # https://peps.python.org/pep-0703/#build-configuration-changes
         "gil_disabled": bool(sysconfig.get_config_var("Py_GIL_DISABLED")),

crates/uv-python/src/interpreter.rs

@@ -33,6 +33,7 @@ pub struct Interpreter {
     markers: Box<MarkerEnvironment>,
     scheme: Scheme,
     virtualenv: Scheme,
+    manylinux_compatible: bool,
     sys_prefix: PathBuf,
     sys_base_exec_prefix: PathBuf,
     sys_base_prefix: PathBuf,
@@ -63,6 +64,7 @@ impl Interpreter {
             markers: Box::new(info.markers),
             scheme: info.scheme,
             virtualenv: info.virtualenv,
+            manylinux_compatible: info.manylinux_compatible,
             sys_prefix: info.sys_prefix,
             sys_base_exec_prefix: info.sys_base_exec_prefix,
             pointer_size: info.pointer_size,
@@ -176,6 +178,7 @@ impl Interpreter {
                 self.python_tuple(),
                 self.implementation_name(),
                 self.implementation_tuple(),
+                self.manylinux_compatible,
                 self.gil_disabled,
             )?;
             self.tags.set(tags).expect("tags should not be set");
@@ -373,6 +376,11 @@ impl Interpreter {
         &self.virtualenv
     }
 
+    /// Return whether this interpreter is `manylinux` compatible.
+    pub fn manylinux_compatible(&self) -> bool {
+        self.manylinux_compatible
+    }
+
     /// Return the [`PointerSize`] of the Python interpreter (i.e., 32- vs. 64-bit).
     pub fn pointer_size(&self) -> PointerSize {
         self.pointer_size
@@ -555,6 +563,7 @@ struct InterpreterInfo {
     markers: MarkerEnvironment,
     scheme: Scheme,
     virtualenv: Scheme,
+    manylinux_compatible: bool,
     sys_prefix: PathBuf,
     sys_base_exec_prefix: PathBuf,
     sys_base_prefix: PathBuf,
@@ -785,6 +794,7 @@ mod tests {
                     },
                     "arch": "x86_64"
                 },
+                "manylinux_compatible": false,
                 "markers": {
                     "implementation_name": "cpython",
                     "implementation_version": "3.12.0",

crates/uv-python/src/lib.rs

@@ -210,6 +210,7 @@ mod tests {
                             },
                             "arch": "x86_64"
                         },
+                        "manylinux_compatible": true,
                         "markers": {
                             "implementation_name": "{IMPLEMENTATION}",
                             "implementation_version": "{FULL_VERSION}",

crates/uv/src/commands/pip/mod.rs

@@ -29,20 +29,23 @@ pub(crate) fn resolution_environment(
             (python_version.major(), python_version.minor()),
             interpreter.implementation_name(),
             interpreter.implementation_tuple(),
+            interpreter.manylinux_compatible(),
             interpreter.gil_disabled(),
         )?),
         (Some(python_platform), None) => Cow::Owned(Tags::from_env(
             &python_platform.platform(),
             interpreter.python_tuple(),
             interpreter.implementation_name(),
             interpreter.implementation_tuple(),
+            interpreter.manylinux_compatible(),
             interpreter.gil_disabled(),
         )?),
         (None, Some(python_version)) => Cow::Owned(Tags::from_env(
             interpreter.platform(),
             (python_version.major(), python_version.minor()),
             interpreter.implementation_name(),
             interpreter.implementation_tuple(),
+            interpreter.manylinux_compatible(),
             interpreter.gil_disabled(),
         )?),
         (None, None) => Cow::Borrowed(interpreter.tags()?),

docs/pip/compatibility.md

@@ -346,6 +346,34 @@ reuse any binary distributions that are already present in the local cache.
 Additionally, and in contrast to pip, uv's resolver will still read metadata from pre-built binary
 distributions when `--no-binary` is provided.
 
+## `manylinux_compatible` enforcement
+
+[PEP 600](https://peps.python.org/pep-0600/#package-installers) describes a mechanism through which
+Python distributors can opt out of `manylinux` compatibility by defining a `manylinux_compatible`
+function on the `_manylinux` standard library module.
+
+uv respects `manylinux_compatible`, but only tests against the current glibc version, and applies
+the return value of `manylinux_compatible` globally.
+
+In other words, if `manylinux_compatible` returns `True`, uv will treat the system as
+`manylinux`-compatible; if it returns `False`, uv will treat the system as `manylinux`-incompatible,
+without calling `manylinux_compatible` for every glibc version.
+
+This approach is not a complete implementation of the spec, but is compatible with common blanket
+`manylinux_compatible` implementations like
+[`no-manylinux`](https://pypi.org/project/no-manylinux/):
+
+```python
+from __future__ import annotations
+manylinux1_compatible = False
+manylinux2010_compatible = False
+manylinux2014_compatible = False
+
+
+def manylinux_compatible(*_, **__):  # PEP 600
+    return False
+```
+
 ## Bytecode compilation
 
 Unlike pip, uv does not compile `.py` files to `.pyc` files during installation by default (i.e., uv