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27 changes: 26 additions & 1 deletion ontology/chebi.md
Original file line number Diff line number Diff line change
Expand Up @@ -20,6 +20,10 @@ license:
domain: biochemistry
homepage: http://www.ebi.ac.uk/chebi
page: http://www.ebi.ac.uk/chebi/init.do?toolBarForward=userManual
depicted_by: https://www.ebi.ac.uk/chebi/images/ChEBI_logo.png
publications:
- id: http://europepmc.org/article/MED/26467479
title: "ChEBI in 2016: Improved services and an expanding collection of metabolites."
browsers:
- label: CHEBI
title: EBI CHEBI Browser
Expand All @@ -34,7 +38,28 @@ products:
- id: chebi/chebi_core.obo
title: "chebi_core, no xrefs"
tracker: https://github.com/ebi-chebi/ChEBI/issues
usages:
- user: https://www.rhea-db.org/
description: Rhea uses CHEBI to annotate reaction participants
examples:
- url: https://www.rhea-db.org/searchresults?q=CHEBI:29748
description: "Query for all usages of CHEBI:29748 (chorismate)"
- user: http://zfin.org
description: ZFIN uses CHEBI to annotate experiments
examples:
- url: http://zfin.org/action/expression/experiment?id=ZDB-EXP-190627-10
description: "A curated zebrafish experiment involving exposure to (5Z,8Z,14Z)-11,12-dihydroxyicosatrienoic acid (CHEBI:63969)"
activity_status: active
---

A structured classification of chemical compounds of biological relevance.
A freely available dictionary of molecular entities focused on ‘small’ chemical compounds.
The term ‘molecular entity’ refers to any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer, etc., identifiable as a separately distinguishable entity. The molecular entities in question are either products of nature or synthetic products used to intervene in the processes of living organisms.

ChEBI incorporates an ontological classification, whereby the relationships between molecular entities or classes of entities and their parents and/or children are specified.

ChEBI uses nomenclature, symbolism and terminology endorsed by the following international scientific bodies:

- International Union of Pure and Applied Chemistry (IUPAC)
- Nomenclature Committee of the International Union of Biochemistry and Molecular Biology (NC-IUBMB)

Molecules directly encoded by the genome (e.g. nucleic acids, proteins and peptides derived from proteins by cleavage) are not as a rule included in ChEBI.