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LP.8.1.8 + S:T22N (142, >10 Places) with a S:D80G (13, 3 places) branch that gained further ORF1b:P2313S, S:W64G, N:R204P ( 10, 3 Places) #2941

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FedeGueli opened this issue Apr 28, 2025 · 4 comments
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LP.8.1.8 + S:T22N (142, >10 Places) with a S:D80G (13, 3 places) branch that gained further ORF1b:P2313S, S:W64G, N:R204P ( 10, 3 Places) #2941

FedeGueli opened this issue Apr 28, 2025 · 4 comments

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@FedeGueli
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FedeGueli commented Apr 28, 2025 •
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LP.8.1.8 + S:T22N
LP.8.1.8>> S:T22N (C21627A) >> S:D80G (A21801G) > N:R204P (G28884C) >> ORF1b:P2313S (C20404T), S:W64G (T21752G)
Query: C21627A,C28674T,C4999T
Samples: 113 ( US-8 States, Germany, Canada)

with a S:D80G branch
Query: A21801G,C28674T,C4999T
Samples: 11 (US- Germany-Canada)

and a further S:W64G + N:R204P branch spotted by @ryhisner
Query: T21752G,C20404T,A21801G
Samples:9 (US-Germany-Canada)

Tree:
https://nextstrain.org/fetch/genome.ucsc.edu/trash/hgPhyloPlace/subtreeAuspice1_genome_3a314d_f4f070.json?label=id:node_7446293
Image

IDs

General branch EPI_ISL_19657167, EPI_ISL_19658511, EPI_ISL_19666138, EPI_ISL_19668199, EPI_ISL_19673493, EPI_ISL_19673507, EPI_ISL_19678471, EPI_ISL_19703442, EPI_ISL_19715689, EPI_ISL_19716430, EPI_ISL_19716600, EPI_ISL_19716873, EPI_ISL_19727357, EPI_ISL_19727393, EPI_ISL_19739446, EPI_ISL_19739526, EPI_ISL_19739647, EPI_ISL_19749328, EPI_ISL_19749711, EPI_ISL_19749791, EPI_ISL_19749934, EPI_ISL_19749952, EPI_ISL_19751212, EPI_ISL_19757404, EPI_ISL_19760185, EPI_ISL_19760240, EPI_ISL_19760257, EPI_ISL_19760377, EPI_ISL_19760422, EPI_ISL_19763696, EPI_ISL_19765220, EPI_ISL_19765250, EPI_ISL_19765307, EPI_ISL_19771501, EPI_ISL_19771526, EPI_ISL_19771544, EPI_ISL_19771562, EPI_ISL_19771570, EPI_ISL_19771602, EPI_ISL_19773157, EPI_ISL_19780379-19780380, EPI_ISL_19780427, EPI_ISL_19780458, EPI_ISL_19783990, EPI_ISL_19784044, EPI_ISL_19784151, EPI_ISL_19784195, EPI_ISL_19784233, EPI_ISL_19792780, EPI_ISL_19792815, EPI_ISL_19792829, EPI_ISL_19792868, EPI_ISL_19792932, EPI_ISL_19792979, EPI_ISL_19795174, EPI_ISL_19795217-19795218, EPI_ISL_19795222, EPI_ISL_19795233, EPI_ISL_19795386, EPI_ISL_19801954, EPI_ISL_19804260, EPI_ISL_19804720, EPI_ISL_19820159, EPI_ISL_19820217, EPI_ISL_19820224, EPI_ISL_19820231, EPI_ISL_19821745, EPI_ISL_19821900, EPI_ISL_19821923, EPI_ISL_19821936, EPI_ISL_19825292, EPI_ISL_19826518, EPI_ISL_19826542, EPI_ISL_19826546, EPI_ISL_19826580, EPI_ISL_19826616, EPI_ISL_19826636, EPI_ISL_19829091, EPI_ISL_19829096, EPI_ISL_19829104, EPI_ISL_19829127, EPI_ISL_19832696, EPI_ISL_19836426, EPI_ISL_19836436, EPI_ISL_19836444, EPI_ISL_19836467, EPI_ISL_19836552, EPI_ISL_19836578, EPI_ISL_19836600, EPI_ISL_19836618, EPI_ISL_19842990, EPI_ISL_19843000, EPI_ISL_19843026, EPI_ISL_19843148, EPI_ISL_19843284, EPI_ISL_19849856, EPI_ISL_19849874, EPI_ISL_19849908, EPI_ISL_19849912, EPI_ISL_19849915
S:D80G Branch EPI_ISL_19749816, EPI_ISL_19773208, EPI_ISL_19792888, EPI_ISL_19829095
S:W64G branch EPI_ISL_19825260, EPI_ISL_19826621, EPI_ISL_19829146, EPI_ISL_19836584, EPI_ISL_19849142, EPI_ISL_19849161, EPI_ISL_19849876
@FedeGueli FedeGueli mentioned this issue Apr 28, 2025
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@FedeGueli FedeGueli changed the title LP.8.1.8 + S:T22N (113, 2 Places) with a S:D80G (11, 2 places) branch that gained further ORF1b:P2313S, S:W64G, N:R204P ( 8, 2 Places) LP.8.1.8 + S:T22N (120, 10 Places) with a S:D80G (12, 3 places) branch that gained further ORF1b:P2313S, S:W64G, N:R204P ( 9, 3 Places) Apr 30, 2025
@FedeGueli
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120 with one more in the 80G/64G branch cc @ryhisner

@FedeGueli FedeGueli changed the title LP.8.1.8 + S:T22N (120, 10 Places) with a S:D80G (12, 3 places) branch that gained further ORF1b:P2313S, S:W64G, N:R204P ( 9, 3 Places) LP.8.1.8 + S:T22N (122, >10 Places) with a S:D80G (12, 3 places) branch that gained further ORF1b:P2313S, S:W64G, N:R204P ( 9, 3 Places) May 4, 2025
@FedeGueli
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cc @corneliusroemer this should be designated

@FedeGueli FedeGueli changed the title LP.8.1.8 + S:T22N (122, >10 Places) with a S:D80G (12, 3 places) branch that gained further ORF1b:P2313S, S:W64G, N:R204P ( 9, 3 Places) LP.8.1.8 + S:T22N (134, >10 Places) with a S:D80G (12, 3 places) branch that gained further ORF1b:P2313S, S:W64G, N:R204P ( 9, 3 Places) May 7, 2025
@FedeGueli
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134 for T22N, the D80G branch maybe has been a cluster luckily

@FedeGueli FedeGueli changed the title LP.8.1.8 + S:T22N (134, >10 Places) with a S:D80G (12, 3 places) branch that gained further ORF1b:P2313S, S:W64G, N:R204P ( 9, 3 Places) LP.8.1.8 + S:T22N (140, >10 Places) with a S:D80G (12, 3 places) branch that gained further ORF1b:P2313S, S:W64G, N:R204P ( 9, 3 Places) May 11, 2025
@FedeGueli
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140 maybe slowing down

@FedeGueli FedeGueli changed the title LP.8.1.8 + S:T22N (140, >10 Places) with a S:D80G (12, 3 places) branch that gained further ORF1b:P2313S, S:W64G, N:R204P ( 9, 3 Places) LP.8.1.8 + S:T22N (142, >10 Places) with a S:D80G (13, 3 places) branch that gained further ORF1b:P2313S, S:W64G, N:R204P ( 10, 3 Places) May 12, 2025
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