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Lineage BR.5.1 Notes Errata #2048

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alurqu opened this issue Jun 10, 2023 · 1 comment
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Lineage BR.5.1 Notes Errata #2048

alurqu opened this issue Jun 10, 2023 · 1 comment

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@alurqu
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alurqu commented Jun 10, 2023

The commit log and lineage notes show "ORF1b:T5923I" as a defining mutation for BR.5.1. This residue position is too large. Was "ORF1ab:T5923I" intended? This would be ORF1b:T1522I.

The listed mutations BR.5 + ORF1a:K2029N, ORF1b:T5923I, A20289G cause an error on CoV-Spectrum. However, BR.5 + ORF1a:K2029N, ORF1b:T5923I, A20289G returns approximately the expected number of sequences mostly from South Korea.

@Walde1nsamkeit
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It is actually ORF1ab:T5923I, namely ORF1b:T1522I.

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