diff --git a/changelog.d/11939.misc b/changelog.d/11939.misc
new file mode 100644
index 000000000000..317526f9efb4
--- /dev/null
+++ b/changelog.d/11939.misc
@@ -0,0 +1 @@
+Remove an unnecessary ignoring of type hints due to fixes in upstream packages.
diff --git a/synapse/handlers/send_email.py b/synapse/handlers/send_email.py
index 1a062a784cd4..a305a66860a5 100644
--- a/synapse/handlers/send_email.py
+++ b/synapse/handlers/send_email.py
@@ -106,7 +106,7 @@ def build_sender_factory(**kwargs: Any) -> ESMTPSenderFactory:
         factory = build_sender_factory(hostname=smtphost if enable_tls else None)
 
     reactor.connectTCP(
-        smtphost,  # type: ignore[arg-type]
+        smtphost,
         smtpport,
         factory,
         timeout=30,
diff --git a/synapse/replication/tcp/handler.py b/synapse/replication/tcp/handler.py
index 21293038ef84..f7e6bc1e6282 100644
--- a/synapse/replication/tcp/handler.py
+++ b/synapse/replication/tcp/handler.py
@@ -318,7 +318,7 @@ def start_replication(self, hs: "HomeServer"):
                 hs, outbound_redis_connection
             )
             hs.get_reactor().connectTCP(
-                hs.config.redis.redis_host,  # type: ignore[arg-type]
+                hs.config.redis.redis_host,
                 hs.config.redis.redis_port,
                 self._factory,
                 timeout=30,
@@ -330,7 +330,7 @@ def start_replication(self, hs: "HomeServer"):
             host = hs.config.worker.worker_replication_host
             port = hs.config.worker.worker_replication_port
             hs.get_reactor().connectTCP(
-                host,  # type: ignore[arg-type]
+                host,
                 port,
                 self._factory,
                 timeout=30,
diff --git a/synapse/replication/tcp/redis.py b/synapse/replication/tcp/redis.py
index 8d28bd3f3fcc..5b37f379d040 100644
--- a/synapse/replication/tcp/redis.py
+++ b/synapse/replication/tcp/redis.py
@@ -373,7 +373,7 @@ def lazyConnection(
 
     reactor = hs.get_reactor()
     reactor.connectTCP(
-        host,  # type: ignore[arg-type]
+        host,
         port,
         factory,
         timeout=30,