diff --git a/CHANGELOG.md b/CHANGELOG.md
index 0856bda6d5..b6dd3546c9 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -1,5 +1,11 @@
 # Changelog
 
+## Unreleased
+
+### Fixes
+
+- `browserReplayIntegration` is no longer included by default on React Native Web ([#4270](https://github.com/getsentry/sentry-react-native/pull/4270), [#4308](https://github.com/getsentry/sentry-react-native/pull/4308))
+
 ## 5.35.0
 
 ### Fixes
diff --git a/src/js/integrations/default.ts b/src/js/integrations/default.ts
index bcbac5c2cb..29369b3dad 100644
--- a/src/js/integrations/default.ts
+++ b/src/js/integrations/default.ts
@@ -10,7 +10,6 @@ import {
   browserApiErrorsIntegration,
   browserGlobalHandlersIntegration,
   browserLinkedErrorsIntegration,
-  browserReplayIntegration,
   debugSymbolicatorIntegration,
   dedupeIntegration,
   deviceContextIntegration,
@@ -120,10 +119,13 @@ export function getDefaultIntegrations(options: ReactNativeClientOptions): Integ
     (options._experiments && typeof options._experiments.replaysOnErrorSampleRate === 'number') ||
     (options._experiments && typeof options._experiments.replaysSessionSampleRate === 'number')
   ) {
-    integrations.push(notWeb() ? mobileReplayIntegration() : browserReplayIntegration());
     if (!notWeb()) {
+      // We can't create and add browserReplayIntegration as it overrides the users supplied one
+      // The browser replay integration works differently than the rest of default integrations
       (options as BrowserOptions).replaysOnErrorSampleRate = options._experiments.replaysOnErrorSampleRate;
       (options as BrowserOptions).replaysSessionSampleRate = options._experiments.replaysSessionSampleRate;
+    } else {
+      integrations.push(mobileReplayIntegration());
     }
   }
 
diff --git a/test/sdk.test.ts b/test/sdk.test.ts
index 0593ba1667..9921289a0e 100644
--- a/test/sdk.test.ts
+++ b/test/sdk.test.ts
@@ -648,6 +648,96 @@ describe('Tests the SDK functionality', () => {
 
     expect(actualIntegrations).toEqual(expect.arrayContaining([expect.objectContaining({ name: 'ExpoContext' })]));
   });
+
+  it('adds mobile replay integration when _experiments.replaysOnErrorSampleRate is set', () => {
+    init({
+      _experiments: {
+        replaysOnErrorSampleRate: 1.0,
+      },
+    });
+
+    const actualOptions = usedOptions();
+    const actualIntegrations = actualOptions?.integrations;
+    expect(actualIntegrations).toEqual(expect.arrayContaining([expect.objectContaining({ name: 'MobileReplay' })]));
+  });
+
+  it('adds mobile replay integration when _experiments.replaysSessionSampleRate is set', () => {
+    init({
+      _experiments: {
+        replaysSessionSampleRate: 1.0,
+      },
+    });
+
+    const actualOptions = usedOptions();
+    const actualIntegrations = actualOptions?.integrations;
+    expect(actualIntegrations).toEqual(expect.arrayContaining([expect.objectContaining({ name: 'MobileReplay' })]));
+  });
+
+  it('does not add mobile replay integration when no replay sample rates are set', () => {
+    init({
+      _experiments: {},
+    });
+
+    const actualOptions = usedOptions();
+    const actualIntegrations = actualOptions?.integrations;
+    expect(actualIntegrations).toEqual(expect.not.arrayContaining([expect.objectContaining({ name: 'MobileReplay' })]));
+  });
+
+  it('does not add any replay integration when on web even with on error sample rate', () => {
+    (notWeb as jest.Mock).mockImplementation(() => false);
+    init({
+      _experiments: {
+        replaysOnErrorSampleRate: 1.0,
+      },
+    });
+
+    const actualOptions = usedOptions();
+    const actualIntegrations = actualOptions?.integrations;
+    expect(actualIntegrations).toEqual(expect.not.arrayContaining([expect.objectContaining({ name: 'Replay' })]));
+    expect(actualIntegrations).toEqual(expect.not.arrayContaining([expect.objectContaining({ name: 'MobileReplay' })]));
+  });
+
+  it('does not add any replay integration when on web even with session sample rate', () => {
+    (notWeb as jest.Mock).mockImplementation(() => false);
+    init({
+      _experiments: {
+        replaysSessionSampleRate: 1.0,
+      },
+    });
+
+    const actualOptions = usedOptions();
+    const actualIntegrations = actualOptions?.integrations;
+    expect(actualIntegrations).toEqual(expect.not.arrayContaining([expect.objectContaining({ name: 'Replay' })]));
+    expect(actualIntegrations).toEqual(expect.not.arrayContaining([expect.objectContaining({ name: 'MobileReplay' })]));
+  });
+
+  it('does not add any replay integration when on web', () => {
+    (notWeb as jest.Mock).mockImplementation(() => false);
+    init({});
+
+    const actualOptions = usedOptions();
+    const actualIntegrations = actualOptions?.integrations;
+    expect(actualIntegrations).toEqual(expect.not.arrayContaining([expect.objectContaining({ name: 'Replay' })]));
+    expect(actualIntegrations).toEqual(expect.not.arrayContaining([expect.objectContaining({ name: 'MobileReplay' })]));
+  });
+
+  it('converts experimental replay options to standard web options when on web', () => {
+    (notWeb as jest.Mock).mockImplementation(() => false);
+    init({
+      _experiments: {
+        replaysOnErrorSampleRate: 0.5,
+        replaysSessionSampleRate: 0.1,
+      },
+    });
+
+    const actualOptions = usedOptions();
+    expect(actualOptions).toEqual(
+      expect.objectContaining({
+        replaysOnErrorSampleRate: 0.5,
+        replaysSessionSampleRate: 0.1,
+      }),
+    );
+  });
 });
 
 function createMockedIntegration({ name }: { name?: string } = {}): Integration {